Oregon Health & Science University (OHSU) School of Medicine, Department of Molecular & Medical Genetics(オレゴン州ポートランド)Nakai研究室では、adeno-associated virus (AAV) のウィルス学的研究とおよびAAV を用いた新しい遺伝子治療研究を中心となって進めて頂けるポスドクを2名募集しています。採用期間は複数年です。
Two postdoctoral researcher positions for multiple years, supported by NIH and other non-federal grants, are immediately available in the Hiroyuki Nakai laboratory in the Department of Molecular and Medical Genetics, Oregon Health & Science University (OHSU). The Nakai lab studies adeno-associated virus (AAV) and its application for gene therapy using in vitro tissue culture models and in vivo models including mice, cats and non-human primates. In particular, the Nakai lab takes non-traditional multi-disciplinary approaches to study AAV viral proteins and virus-host interactions using the high-throughput next-generation sequencing (NGS) technology, barcoding, computer simulation and modeling, bioinformatics and biostatistics in addition to the traditional low-throughput structural and functional biology-based approaches, in collaboration with experts in each relevant field. In addition, the Nakai lab studies novel functions of assembly activating protein (AAP), a newly discovered, non-structural AAV protein whose role appeared to be more than promoting capsid assembly. Ultimately, the lab will develop the next generation gene delivery vector systems that are more ideal for human gene therapy based on much deeper understanding of AAV than ever. By applying the new technologies that have been and will be developed in his lab, the Nakai lab tries to establish new approaches to treat diseases in the central nervous system (CNS), diabetes and genetic diseases and control reproduction in collaboration with investigators across and outside the university. In addition, the Nakai lab has had strong passion for addressing any unanswered questions in fundamental biological processes not directly relevant to AAV or gene therapy.
[ 採用人数]ポスドク2名
[採用期間]2年ないしはそれ以上 。
[給与]$42,840〜
[ 資格 ]分子生物学、細胞生物学実験の経験を十分にもち、上記研究に興味のある医師、獣医師、博士号取得(見込)者。
[応募締切]該当者が決まり次第締め切ります。
[応募方法] Hiroyuki Nakai(nakaih@ohsu.edu)までご連絡下さい。詳細をお知らせ致します。また、質問も受け付けます(日本語可)。
Hiroyuki Nakai, M.D., Ph.D.
Associate Professor
Department of Molecular & Medical Genetics
Oregon Health & Science University School of Medicine
Associate Scientist
Division of Neuroscience
Oregon National Primate Research Center
Email: nakaih@ohsu.edu
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